from The American Heritage® Dictionary of the English Language, 4th Edition
- n. A protease-inhibiting drug usually used in combination with other drugs to suppress the replication of HIV.
from Wiktionary, Creative Commons Attribution/Share-Alike License
- n. An anti-retroviral drug of the protease inhibitor class that is used in to treat HIV infected patients.
from WordNet 3.0 Copyright 2006 by Princeton University. All rights reserved.
- n. a protease inhibitor (trade name Viracept) used in treating HIV usually in combination with other drugs
Researchers at the Tulane University School of Medicine, New Orleans, Louisiana have discovered that the HIV-1 protease inhibitors (PIs), such as nelfinavir included in highly active antiretroviral therapy (HAART) regimen for the treatment of HIV-1 patients, induce deleterious effects on insulin secretion mediated through the oxidative stress pathway.
Importantly, the team found that EGCG only reacted with proteasome inhibitors that have a boronic acid base (including bortezomib) but did not react with several non-boronic acid-based proteasome inhibitors (such as nelfinavir [Viracept (R)], a treatment for HIV).
Importantly, the team found that EGCG only reacted with proteasome inhibitors that have a boronic acid base (including bortezomib) but did not react with several non-boronic acid-based proteasome inhibitors (such as nelfinavir [Viracept®], a treatment for HIV).
In August 2001, Brazilian Health Minister Jose Serra announced the Brazilian government would issue a compulsory license for the manufacture of the antiretroviral drug nelfinavir, whose brand name was Viracept.
And Agouron Pharmaceuticals will soon seek approval for nelfinavir, the first protease inhibitor formulated for children as well as adults.
Therapies which included nelfinavir (Viracept), amprenavir
The Brazilian government has decided that Roche is charging too much money for their AIDS-fighting drug nelfinavir, and since Roche wouldn't knock the price down, the Brazilian government has decided to simply clone the drug, essentially asserting that human lives are more important that patent-treaties.
In the U.S. trial, a further drug - nelfinavir - was combined with lamivudine and AZT, and appeared to not only slow progression to the full-blown disease but to reduce the levels of the HIV virus in the blood, Lancet reported.
Pfizer is advising healthcare professionals to avoid treating certain children and pregnant women with the antiretroviral drug Viracept (nelfinavir mesylate).
The simulation included isopropanol solvent recovery from the manufacture of nelfinavir, the active ingredient in the antiretroviral drug VIRACEPT®, used in the treatment of the human immunodeficiency virus (HIV).
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