Definitions

from Wiktionary, Creative Commons Attribution/Share-Alike License.

  • adjective Of or pertaining to a nucleosome

Etymologies

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Examples

  • Most recently, we found that RSC can transfer a histone octamer to a histone chaperone protein, exposing the nucleosomal DNA for transactions such as transcription

    Roger D. Kornberg - Autobiography 2007

  • Wild type cells show a nucleosomal deprived region around the transcriptional start site at methylated Hox genes and mediate gene silencing via Pol II stalling.

    PLoS ONE Alerts: New Articles Yongguang Tao et al. 2010

  • To address the molecular mechanism of Hox gene silencing in dependence of Lsh and DNA methylation we examined nucleosomal positioning,

    PLoS ONE Alerts: New Articles Yongguang Tao et al. 2010

  • Liang G, Takai D, Fatemi M, et al. (2007) Role of nucleosomal occupancy in the epigenetic silencing of the MLH1 CpG island.

    PLoS ONE Alerts: New Articles Yongguang Tao et al. 2010

  • Furthermore, Lsh is a homologue of SNF2 factors and may affect nucleosomal positioning at HoxC genes; although Lsh has not been demonstrated, as yet, to posses nucleosomal remodeling activity.

    PLoS ONE Alerts: New Articles Yongguang Tao et al. 2010

  • In addition, a recent study demonstrated nucleosomal positioning at the transcriptional start site of the human MLH1 promoter in dependence of DNA methylation thus precluding Pol II binding

    PLoS ONE Alerts: New Articles Yongguang Tao et al. 2010

  • Phased nucleosomal positioning at TSS or enhancer elements is associated with active transcription, and regular nucleosomal pattern have been found at Hox clusters

    PLoS ONE Alerts: New Articles Yongguang Tao et al. 2010

  • Wild type cells show a nucleosomal deprived region around the transcriptional start site at methylated Hox genes and mediate gene silencing via Pol II stalling.

    PLoS ONE Alerts: New Articles Yongguang Tao et al. 2010

  • The effect of DNA methylation was enhancing as well as preventing nucleosomal occupancy (for example at the chicken beta globin locus) making it necessary to examine nucleosomal position at the individual promoter level

    PLoS ONE Alerts: New Articles Yongguang Tao et al. 2010

  • To address the molecular mechanism of Hox gene silencing in dependence of Lsh and DNA methylation we examined nucleosomal positioning,

    PLoS ONE Alerts: New Articles Yongguang Tao et al. 2010

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