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“It has no relevance to abiogenesis, "no known biological nucleotide-binding domain is a zinc-stabilized structure.”
“Guts: It has no relevance to abiogenesis, "no known biological nucleotide-binding domain is a zinc-stabilized structure.”
“Zhang and colleagues (Dec. 31 issue) 1 report that genes in the nucleotide-binding oligomerization domain containing 2 (NOD2) - mediated signaling pathway are associated with susceptibility to infection with Mycobacterium leprae in China.”
“They also have a nucleotide-binding site in common.”
“MamK is closely related to the MreB family: it has a nucleotide-binding site and polymerizes into filaments that assemble into bundles extending from one pole of the cell to the other.”
“In addition, key residues putatively involved in the nucleotide-binding site are conserved”
“Both belong to the family of ABC transporters containing two nucleotide-binding subunits, two integral membrane proteins and one substrate-binding polypeptide.”
“NBS-LRR family genes encode plant disease resistance (R) proteins with a nucleotide-binding site (NBS), a series of leucine-rich repeats (LRRs) .”
“Since accumulation of full-length Irgm1 on phagosomes depended on the integrity of the nucleotide-binding motif, it seems that another GTP-dependent conformationally active region of full-length Irgm1 must contribute to the phagosomal accumulation of the protein.”
“(C) The same experiments were performed as in (B) but using the nucleotide-binding deficient mutants (S90N) of N - and C-terminally EGFP-tagged Irgm1.”
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