American Heritage® Dictionary of the English Language, Fourth Edition
- n. Dissolution or degeneration of bone tissue through disease.
Century Dictionary and Cyclopedia
- n. Softening and disintegration of bone.
GNU Webster's 1913
- n. Softening and absorption of bone.
- n. lysis of bone caused by disease or infection or inadequate blood supply
- osteo- + -lysis (Wiktionary)
“The body mounts a cellular reaction to try to deal with the wear debris, a reaction that unfortunately often leads to unwanted destruction of bone (called osteolysis) around the implant," he wrote in the report.”
“The drug halted the infection within one day of treatment, preventing the development of osteolysis, bone breakdown associated with joint-replacement failure.”
“Training and research focus on (a) an evolutionary perspective in the analysis of morphology, including the influences of function, structure, and phylogenetic history, and (b) the structural adaptations of bone as load-bearing tissue, including the physiologic mechanisms of osteogenesis and osteolysis.”
“Polyethylene particulate debris-induced periprosthetic osteolysis is a known complication of knee arthroplasty surgery, and may result in the need for revision surgery.”
“We present the case of a 71 year old man who developed knee pain and osteolysis around an uncemented total knee replacement.”
“Bisphosphonates (BPs) had long been used in metabolic bone disease as osteoporosis, tumor-associated hypercalcaemia and metastases-induced osteolysis due to their ability to inhibit bone resorption.”
“Also, with time, the number of surgical revisions has increased due to osteolysis, or bone resorption as a result of the body's reaction to debris created by wear and corrosion of the metal implants.”
“Besides the difficulty of mimicking these functions, designers of replacement joints also have the added challenge of inserting a flange (a type of rod) into the ulna, a small bone in the lower arm that is prone to osteolysis or dissolving.”
“The former index presumably reflects the key role of inhibition of osteolysis after 186Re-HEDP treatment for achievement of improved response.”
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