“This process requires the functions of various molecules including the transmembrane myoblast attractants Dumbfounded (Duf) and its paralogue Roughest (Rst), a scaffold protein Rolling pebbles (Rols) and a guanine nucleotide exchange factor Loner.”
“Strunkelnberg M, Bonengel B, Moda LM, Hertenstein A, de Couet HG, et al. (2001) rst and its paralogue kirre act redundantly during embryonic muscle development in Drosophila.”
“The FCs express the myoblast attractants, Dumbfounded (Duf)/Kin of irregular-chiasm-C (Kirre) and its paralogue Roughest (Rst)/Irregular chiasm-C (IrreC)”
“There are examples of other paralogue genes in zebrafish showing differences in expression patterns”
“Researchers have therefore increased the severity of the murine dystrophin-deficiency phenotype by creating double mutants: either mice lacking both dystrophin and its paralogue, utrophin, or both dystrophin and MyoD (a transcription factor important in muscle development and regeneration) , .”
“Molecular evolutionary analyses indicated that: rln3a, rln3b and rln are under strong evolutionary constraint, that insl3 has been subject to moderate rates of sequence evolution with two amino acids in insl3/INSL3 showing evidence of positively selection, and that insl5b exhibits a higher rate of sequence evolution than its paralogue insl5a suggesting that it may have been neo-functionalized after the teleost whole genome duplication.”
“The homB gene is a Helicobacter pylori disease marker candidate, strongly associated with peptic ulcer disease, while homA, its paralogue gene with 90% sequence identity, is correlated with non ulcer dyspepsia.”
“Six homologues of cold shock proteins (CspA, − B, C, D, G, H, I), among which two copies of cspC were included, were discerned to represent one of the largest paralogue gene family in EIB202.”
“Keren-Paz A, Bercovich Z, Kahana C (2008) ODCp, a brain - and testis-specific ornithine decarboxylase paralogue, functions as an antizyme inhibitor, although less efficiently than AzI1.”
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