Definitions

from The American Heritage® Dictionary of the English Language, 4th Edition

  • n. An environmentally induced, nonhereditary variation in an organism, closely resembling a genetically determined trait.

from Wiktionary, Creative Commons Attribution/Share-Alike License

  • n. A variation in an organism that resembles a genetic one, but has an environmental rather than a genetic cause, and is not inherited
  • v. To copy a genetic variation through environmental manipulation

Etymologies

pheno(type) + copy.
(American Heritage® Dictionary of the English Language, Fourth Edition)
pheno- +‎ copy (Wiktionary)

Examples

  • This is called a phenocopy, where an environmental factor induces an effect similar to a genetic mutation.

    It's more than genes, it's networks and systems - The Panda's Thumb

  • The beer analogy is wonderful for explaining phenocopy mutation.

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  • The pathological similarity suggests that epigenetic processes may phenocopy the Familial Alzheimer's disease (FAD) mutations within sporadic AD.

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  • Thus prolonged incubation with HC-056456 produces a phenocopy of the lack-of-hyperactivation phenotype of the CatSper null sperm.

    PLoS ONE Alerts: New Articles

  • In addition to the pharmacological-phenocopy approach used here for study of the roles of CatSper in activation and hyperactivation of motility, we recently applied a chemical-genetic approach to extend our knowledge of the roles of PKA in the these processes.

    PLoS ONE Alerts: New Articles

  • In this and other respects, HC-056456 produces a pharmacological phenocopy of the CatSper-null sperm.

    PLoS ONE Alerts: New Articles

  • We also show that in wild type cells manipulations of sulfur metabolic flux phenocopy the enhanced growth rate of cells with more mtDNA.

    PLoS ONE Alerts: New Articles

  • Consequently, we then examined if adding exogenous sulfur metabolites to wild type cells would phenocopy the enhanced growth rate seen in cells over-expressing Abf2p.

    PLoS ONE Alerts: New Articles

  • Analysis of individual pairs of sister kinetochores confirmed that depletion of condensin appears to phenocopy (

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