Definitions
Wiktionary
- n. biochemistry Any transferase that involves phosphoribosyl pyrophosphate
Examples
“In 1995, (two years after the introduction of 6-MP into clinical use) the enzyme which converts hypoxanthine and 6-MP to their respective nucleotides was identified as phosphoribosyltransferase”
“Production of a model for Lesch-Nyhan syndrome in hypoxanthine phosphoribosyltransferase-deficient mice.”
The 2007 Nobel Prize in Physiology or Medicine - Advanced Information
“He and his co-workers transferred a mutant gene for hypoxanthine phosphoribosyltransferase (HPRT), which is defective in Lesch-Nyhan syndrome, an X-linked monogenic defect of purine metabolism [21].”
The 2007 Nobel Prize in Physiology or Medicine - Advanced Information
“[39] Koller BH, Hagemann LJ, Doetschman T, Hagaman JR, Huang S, Williams PJ, et al. Germ-line transmission of a planned alteration made in a hypoxanthine phosphoribosyltransferase gene by homologous recombination in embryonic stem cells.”
The 2007 Nobel Prize in Physiology or Medicine - Advanced Information
“This prompted analysis of purine salvage pathways in mice and led to the findings that mice depend largely on adenine phosphoribosyltransferase (APRT) for purine salvage and are therefore not as sensitive to HPRT deficiency as humans.”
The 2007 Nobel Prize in Physiology or Medicine - Advanced Information
“Hulambda4x-8, clone: human hypoxanthine phosphoribosyltransferase (HPRT).”
“(ATCC 57057) 2. plambda500, clone: human hypoxanthine phosphoribosyltransferase pseudogene (HPRT).”
“Hulambda15, clone: human hypoxanthine phosphoribosyltransferase (HPRT).”
“PHPT31, clone: human hypoxanthine phosphoribosyltransferase (HPRT).”
“Hulambda14, clone: human hypoxanthine phosphoribosyltransferase (HPRT).”
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