Definitions

from The American Heritage® Dictionary of the English Language, 4th Edition

  • transitive v. To add a phosphate group to (an organic molecule).

from Wiktionary, Creative Commons Attribution/Share-Alike License

  • v. To cause phosphorylation.
  • v. To undergo phosphorylation.

Etymologies

Sorry, no etymologies found.

Examples

  • The glycerol backbone of triglycerides stored in fat cells is ensured of being used as a gluconeogenic substrate since fat cells lack the enzyme that would be needed to phosphorylate the glycerol molecule.

    More on Tierney, Taubes and saturated fat | The Blog of Michael R. Eades, M.D.

  • Some kinases only phosphorylate "downstream" of other phosphosites.

    Prediction of phospho-proteins from sequence

  • If there is no Krebs cycle, no metabolism and no more ATP to phosphorylate peptides in kinase activity etc, then that organism is simply dead — and it is in equilibrium, or is on a monotonic course to equilibrium as it decays or is consumed by other organisms.

    A Dark, Misleading Force

  • They will phosphorylate different proteins and affect the cell nucleus, which in turn will issue orders regarding the synthesis of new proteins.

    Physiology or Medicine for 2000 - Press Release

  • This means that enzymes phosphorylate and dephosphorylate proteins.

    Physiology or Medicine 1992 - Press Release

  • The activity of Akt immunoprecipitated from the cell lysates was determined by its ability to phosphorylate GSK3α.

    PLoS ONE Alerts: New Articles

  • Effect of ROS and RNS modulators on insulin-stimulated Akt activity Although phosphorylation of Ser473 and Thr308 residues is generally used as a marker of Akt activation, we directly measured its enzymatic activity by determining its ability to phosphorylate GSK3α which is one of its known targets.

    PLoS ONE Alerts: New Articles

  • The cleavage product, containing a tyrosine kinase domain, is translocated to the nucleus and is believed to phosphorylate nuclear substrates

    PLoS ONE Alerts: New Articles

  • As CDK4 is known to phosphorylate Rb, and is a known oncogene, the independent oncogenic role of

    PLoS ONE Alerts: New Articles

  • One additional complicating factor is these analyses is the fact that cdc2 has been reported to directly phosphorylate both S6K1

    PLoS ONE Alerts: New Articles

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