Definitions
from The American Heritage® Dictionary of the English Language, 5th Edition.
- noun Any of a group of organic compounds, such as spermine and spermidine, composed of only carbon, nitrogen, and hydrogen and containing two or more amino groups.
from Wiktionary, Creative Commons Attribution/Share-Alike License.
- noun organic chemistry any
compound having many (more than three)amino functional groups ; especially such compounds formed by decomposition ofproteins
Etymologies
from Wiktionary, Creative Commons Attribution/Share-Alike License
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Examples
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Hence, iNOS may down-regulate proline and polyamine production in M1 MØ by competing with Arg II for L-Arg.
PLoS ONE Alerts: New Articles Jamila Khallou-Laschet et al. 2010
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Li H, Meininger CJ, Hawker JR Jr, Haynes TE, Kepka-Lenhart D, et al. (2001) Regulatory role of arginase I and II in nitric oxide, polyamine, and proline syntheses in endothelial cells.
PLoS ONE Alerts: New Articles Jamila Khallou-Laschet et al. 2010
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Polyamines are associated with cell growth and cancer development, and previous research has shown that a polyamine-inhibiting regimen of difluoromethylornithine (DFMO) plus sulindac
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However, they found that DFMO/sulindac treatment only reduced adenoma risk among patients with lower intake of dietary polyamines, and not among those with higher dietary polyamine intake.
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Researchers found that patients with the highest dietary polyamine intake were more likely to have colorectal adenomas greater than 1 cm and advanced adenomas, compared to those with the lowest dietary polyamine intake
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Synthesis and biological evaluation of polyamine toxins as tools for studies of ionotropic glutamate receptors.
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Synthesis and biological evaluation of polyamine toxins as tools for studies of ionotropic glutamate receptors.
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The organic compound spermidine is a polyamine and is found in all living cells.
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Synthesis and biological evaluation of polyamine toxins as tools for studies of ionotropic glutamate receptors.
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They conclude that control of dietary intake of polyamines may be an effective adjunctive strategy to polyamine inhibitors for preventing colorectal adenomas and cancer
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