from The American Heritage® Dictionary of the English Language, 4th Edition
- n. A cluster of ribosomes connected by a strand of messenger RNA and actively synthesizing protein. Also called polysome.
from Wiktionary, Creative Commons Attribution/Share-Alike License
- n. A cluster or ribosomes, connected by mRNA, that collectively synthesizes protein
Sorry, no etymologies found.
Previous work from our lab showed that ZNF9 co-sediments with the polyribosome fractions, suggesting an interaction with the ribosome and a role in translation
To determine if ZNF9 copurifies with human polysomes, lysates from HeLa cells were loaded onto a sucrose cushion and the polyribosome fraction was isolated.
The addition of EDTA disrupts polyribosome formation and is often used as a control to rule out association with other high molecular weight complexes that co-sediment with ribosomes
Examples include a 5 'UTR post-transcriptional control element (PCE), present in at least eight retroviruses, that interacts with cellular RNA helicase A to facilitate cap-dependent polyribosome association; and 3' UTR constitutive transport element
The majority of ZNF9 is found in the pellet (polyribosome) fraction, which suggests that ZNF9 associates with translating ribosomes (
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