American Heritage® Dictionary of the English Language, Fourth Edition
- n. The first stage of syphilis, characterized by formation of a painless chancre at the point of infection and hardening and swelling of adjacent lymph nodes.
GNU Webster's 1913
- adj. (Med.) the initial stage of syphilis, including the period from the development of the original lesion or chancre to the first manifestation of symptoms indicative of general constitutional infection.
- n. the first stage; characterized by a chancre at the site of infection
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