Definitions

from Wiktionary, Creative Commons Attribution/Share-Alike License

  • n. A measure of the average number of nucleotides added by a DNA polymerase enzyme per association/disassociation with the template.

Etymologies

processive +‎ -ity (Wiktionary)

Examples

  • Finally, it was shown to be partially processive, with the polymerase achieving processivity as high as 90% in a few instances.

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  • A template-mutant telomerase that synthesizes DNA that cannot be bound by POT1-TPP1 exhibited increased processivity only when the primer contained at least one POT1-TPP1-binding site, so a single POT1-TPP1-DNA interaction is necessary and sufficient for stimulating processivity.

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  • POT1-TPP1 increased processivity even when substoichiometric relative to the DNA, providing evidence for a recruitment function.

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  • Telomerase contributes to chromosome end replication by synthesizing repeats of telomeric DNA, and the telomeric DNA-binding proteins protection of telomeres (POT1) and TPP1 synergistically increase its repeat addition processivity.

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  • These results support a model in which POT1-TPP1 enhances telomerase processivity in a manner markedly different from the sliding clamps used by DNA polymerases.

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  • POT1-TPP1 enhances telomerase processivity by slowing primer dissociation and aiding translocation

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  • To understand the mechanism of increased processivity, we measured the effect of POT1-TPP1 on individual steps in the telomerase reaction cycle.

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  • RS, Mehta AD, Mooseker MS, Cheney RE, et al. (2000) Myosin-V stepping kinetics: a molecular model for processivity.

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  • Sørbotten A, Synstad B, Sikorski P, Sørlie M, et al. (2006) Endo/exo mechanism and processivity of family 18 chitinases produced by

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  • Therefore, the CID of chiA enhances not only the exo-N, N'-diacetyl-glucosaminidase activity, but also the processivity during the degradation of the polysaccharide chains

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