Definitions

from The American Heritage® Dictionary of the English Language, 4th Edition

  • n. An inactive precursor of a drug, converted into its active form in the body by normal metabolic processes.

from Wiktionary, Creative Commons Attribution/Share-Alike License

  • n. A drug that is administered in an inactive form that is metabolised in the body into a biologically active compound.

Etymologies

pro- +‎ drug (Wiktionary)

Examples

  • It belongs to the class of drugs called prodrug - an inactive compound that is converted into an active drug by the body's metabolic processes.

    Medindia Health News

  • Like many cancer drugs, sunitinib is a "prodrug" that requires the CYP450 family of enzymes in the liver to activate the drug for it to be effective.

    PhysOrg.com - latest science and technology news stories

  • Nektar is developing NKTR-102, a novel prodrug which is a PEGylated form of irinotecan.

    BioSpace.com Featured News and Stories

  • The company also has other advanced drug delivery technologies including Cobalamin (TM) - mediated targeted delivery and oral drug delivery, its proprietary nanopolymer delivery technology based on the natural vitamin B12 uptake mechanism; Angiolix (R), a humanized monoclonal antibody which acts as an anti-angiogenesis factor and is targeted to breast cancer; Prodrax (R), a non-toxic prodrug which is activated in the hypoxic zones of solid tumors to kill cancer cells;

    Health News from Medical News Today

  • The company also has other advanced drug delivery technologies including Cobalamin-mediated targeted delivery and oral drug delivery, its proprietary nanopolymer delivery technology based on the natural vitamin B12 uptake mechanism; Angiolix, a humanized monoclonal antibody which acts as an anti-angiogenesis factor and is targeted to breast cancer; Prodrax, a non-toxic prodrug which is activated in the hypoxic zones of solid tumors to kill cancer cells; Alchemix, a chemotherapeutic agent that combines multiple modes of action to overcome drug resistance.

    Nano Tech Wire

  • Because fosphenytoin is a prodrug and is converted to phenytoin after administration, any concern regarding this association is also applicable to fosphenytoin.

    Caution for Asians on epilepsy drug

  • They do not appear to have any new drug, new prodrug, new method of analyzing for anything.

    The Volokh Conspiracy » Mayo Collaborative Servs. v. Prometheus Laboratories, Inc.

  • They do not appear to have any new drug, new prodrug, new method of analyzing for anything.llQuote

    The Volokh Conspiracy » Mayo Collaborative Servs. v. Prometheus Laboratories, Inc.

  • I spoke in the House of Commons on the CBC prodrug programme, "The Drug Culture," televised a few weeks ago, and of its effect on youths by showing the so-called "joys" of taking drugs, without properly indicating the abject tragedies of this practice -- and the nationdestroying dangers of widespread use, as we saw in the tragic episode of the old China after the opium wars.

    The Spirit of '67

  • For a longer-term future, Gilead is planning the development and commercialization of a future single-tablet regimen combining Prestiza, Emtriva emtricitabine, cobicistat and Gilead's next-generation nucleotide reverse transcriptase inhibitor, GS 7340, a prodrug of tenofovir that is in Phase Ib trials.

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