from Wiktionary, Creative Commons Attribution/Share-Alike License
- adj. Describing any compound or organism involved in neurogenesis
Sorry, no etymologies found.
Of the 24 methylated tumors, 21 fell in the "proneural" signature in which the genes expressed are associated with neural development.
Our genetic evidence from Drosophila and previous in vitro studies of mammalian Atonal homolog 1 (Atoh1, also called Math1 or Hath1) suggest an anti-oncogenic function for the Atonal group of proneural basic helix-loop-helix transcription factors.
It's a proneural gene, which means it activates some part of the embryonic development of the nervous system — in this case, chordotonal organs, cell structures designed to pick up vibrations (think eardrums and the like).
Carmena A, Bate M, Jimenez F (1995) Lethal of scute, a proneural gene, participates in the specification of muscle progenitors during Drosophila embryogenesis.
Mash1 is a proneural transcription factor of the basic helix-loop-helix family, which participates in the commitment of neural progenitors, promotion of cell cycle exit and neuronal migration, and in the final specification of neuronal identities in the brain
The proneural bHLH transcription factor Mash1 was also more strongly expressed in the auditory nerve (AN) of the E18. 5
Hath1) suggest an anti-oncogenic function for the Atonal group of proneural basic helix-loop-helix transcription factors.
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