Definitions
from The American Heritage® Dictionary of the English Language, 5th Edition.
- noun A segment of DNA that resembles a gene but is not functional and usually not transcribed. Pseudogenes often have functional paralogs in the same organism.
from Wiktionary, Creative Commons Attribution/Share-Alike License.
- noun genetics A segment of
DNA that is part of thegenome of anorganism , and which is similar to agene but does not code for a gene product.
Etymologies
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Examples
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Isolation and nucleotide sequence analysis of the beta-type globin pseudogene from human, gorilla and chimpanzee.
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A bit further down in the human pseudogene is a deletion mutation, where one particular letter is missing.
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A bit further down in the human pseudogene is a deletion mutation, where one particular letter is missing.
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Isolation and nucleotide sequence analysis of the beta-type globin pseudogene from human, gorilla and chimpanzee.
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For example, there's what's termed a pseudogene copy of one of the BRCA genes, which has inactivating mutations in it, and no longer produces any protein.
Ars Technica John Timmer 2010
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Usually, that's it, and that copy becomes a so-called pseudogene, functionless litter, part of the famous junk DNA.
Pharyngula 2009
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In the region between the two gamma genes and a gene that works after birth, human DNA contains a broken gene (called a "pseudogene") that closely resembles a working gene for a beta chain, but has features in its sequence that preclude it from coding successfully for a protein.
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In the region between the two gamma genes and a gene that works after birth, human DNA contains a broken gene (called a "pseudogene") that closely resembles a working gene for a beta chain, but has features in its sequence that preclude it from coding successfully for a protein.
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Thus finding a pseudogene in both chimps and humans that has exactly the same mutations in the same places was compelling evidence for him of common ancestry.
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In "The Design of Life" they presented a case in which humans and guinea pigs share the same mistake. (page 133) the GULO pseudogene.
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A pseudogene is what’s been thought of as genetic detritus—a copy of a gene that’s just sitting there, not doing anything productive.
A World Without Pain Condé Nast 2020
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