Definitions
from Wiktionary, Creative Commons Attribution/Share-Alike License.
- noun organic chemistry A naturally occurring,
ultrapotent capsaicin analogue that activates thevanilloid receptor in a subpopulation of primary afferent sensory neurons involved innociception .
Etymologies
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Examples
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Iadarola MJ, Perkowski SZ, Erin H, Shofer F, et al. (2005) Physiologic and antinociceptive effects of intrathecal resiniferatoxin in a canine bone cancer model.
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Use of capsaicin or resiniferatoxin (RTX) as analgesics is an attractive therapeutic option.
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Primary human keratinocytes (NHEK), primary culture of DRG neurons, HaCaT keratinocytes and TRPV1 transformed HaCat keratinocytes were seeded in 96-well plates, then incubated for 10-min with different TRPV1 agonists (capsaicin, CAP; resiniferatoxin, RTX; N-arachidonoyl-dopamine,
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