scrapie

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Taraboulos A, Scott M, Semenov A, Avrahami D, Laszlo L, et al. (1995) Cholesterol depletion and modification of COOH-terminal targeting sequence of the prion protein inhibit formation of the scrapie isoform.

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Definitions (2)

Toggle American Heritage definitions American Heritage Dictionary (1)

  1. noun A usually fatal disease of sheep and goats, marked by chronic itching, loss of muscular coordination, and progressive degeneration of the central nervous system.

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Examples (38)

  • Sheep and goat farmers have participated in a mandatory ID program for about nine years, to rid the us of the spongiform encephalopathy, scrapie, in the same family of diseases as Mad Cow. —  MoJo Blogs and Articles
  • And if our animals had been found to harbor scrapie, why wouldn't we want to get rid to be rid of them, and accept USDA's payment for the culled aimals. —  MoJo Blogs and Articles
  • C to the misfolded, infectious scrapie isoform (PrP Sc) resulting in the conformational conversion of wild-type host alpha-helical, protease sensitive PrP —  PLoS ONE Alerts: New Articles
  • Taraboulos A, Scott M, Semenov A, Avrahami D, Laszlo L, et al. (1995) Cholesterol depletion and modification of COOH-terminal targeting sequence of the prion protein inhibit formation of the scrapie isoform. —  PLoS ONE Alerts: New Articles
  • Vey M, Scott M, Pilkuhn S, Cohen FE, et al. (1997) COOH-terminal sequence of the cellular prion protein directs subcellular trafficking and controls conversion into the scrapie isoform. —  PLoS ONE Alerts: New Articles
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Etymologies (1)

Toggle American Heritage etymologies American Heritage Dictionary (1)

  1. From scrape (from the scraping of itching parts of the skin against objects).
 

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