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Examples

  • They found that single-base changes in a codon are likely to substitute a chemically similar amino acid and therefore make only minimal changes to the final protein.

    An ID Take on the Genetic Code

  • Sure, let's specify translationally silent base substitutions, or single-base substitutions in the middle of big introns, or changes in copy number of wildly polymorphic short tandem repeats, such as those used in paternity testing.

    A Message About ID

  • None of the other teams are doing single-base stunting.

    Cheer!

  • Observation: The genetic code is arranged in a way that minimizes errors, defined as the sum of the differences in amino-acid properties caused by single-base changes from each codon to each other codon.

    The standard genetic code enhances adaptive evolution of proteins - The Panda's Thumb

  • The genetic code is arranged in a way that minimizes errors, defined as the sum of the differences in amino-acid properties caused by single-base changes from each codon to each other codon.

    The standard genetic code enhances adaptive evolution of proteins - The Panda's Thumb

  • We note that this includes both sequence detection errors and artefacts introduced by alignment errors and is approximately ten times worse than the manufacturer's specification of rates of accuracy after dibase correction (99. 94%); independent assessment of single-base accuracy from invalid colour changes suggests that raw sequencing accuracy for these runs was very close to the manufacturer's specification.

    Naturejobs - All Jobs

  • Minister points to another Flaherty single-base hit: the 2007 Working Income Tax Benefit.

    The Globe and Mail - Home RSS feed

  • We found an exceptionally high incidence of single-base mutations in the tumor suppressor genes

    PLoS ONE Alerts: New Articles

  • It is well known that cancer is the result of genetic and epigenetic changes and point mutations is one of the most important mechanisms for the development of cancer Previously, others and we detected numerous single-base changes / mutations in

    PLoS ONE Alerts: New Articles

  • Somatic single-base substitution mutations like the ones found in human tumors in KRAS codons 12 and 13 correspond to SNPs for the cells bearing these mutations, which will appear as heterozygous by any testing (1: 1 ratio for the mutant vs wild-type alleles in mutant cells).

    PLoS ONE Alerts: New Articles

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