Definitions

from The American Heritage® Dictionary of the English Language, 5th Edition.

  • noun Any of a group of peptides that are produced by the liver upon stimulation by growth hormone and act directly on many cell types to stimulate growth.

from Wiktionary, Creative Commons Attribution/Share-Alike License.

  • noun biochemistry Any of a group of peptides which mediate the action of somatotropin on cartilage

Etymologies

from The American Heritage® Dictionary of the English Language, 4th Edition

[Perhaps somato(tropin) + (inter)med(iary) + –in.]

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Examples

  • Insulin-like growth factor also called somatomedin is a protein hormone similar in structure and function to insulin, but with much higher growth-promoting activity than insulin.

    You Being Beautiful Michael F. Roizen 2008

  • Insulin-like growth factor also called somatomedin is a protein hormone similar in structure and function to insulin, but with much higher growth-promoting activity than insulin.

    You Being Beautiful Michael F. Roizen 2008

  • For example, somatomedin or insulin-like growth factor, which mediates the growth-promoting effect of growth hormone, was isolated from human plasma.

    Physiology or Medicine 1986 - Press Release 1986

  • This work led to my appreciation of the role of specific serum factors in the control of cell multiplication and the demonstration that a multiplication-stimulating factor in calf serum for chicken fibroblasts was the same as somatomedin.

    Howard M. Temin - Autobiography 1976

  • For example pituitary gland, helps to stimulate growth through the release of somatomedin.

    CreationWiki - Recent changes [en] 2010

  • For example, pituitary gland, helps to stimulate growth through the release of somatomedin.

    CreationWiki - Recent changes [en] 2010

  • Growth hormone stimulates the release of the hormone somatomedin by the liver, causing growth.

    Health News from Medical News Today 2009

  • The interactions between the two proteins have been attributed primarily to binding of the somatomedin B (SMB) domain, which comprises the N-terminal 44 residues of vitronectin, to the flexible joint region of PAI-1, including residues Arg-103,

    Journal of Biological Chemistry current issue C. R. Schar 2008

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