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- n. The condition of being stereoselective or a measure of the extent to which a reaction is stereoselective
Sorry, no etymologies found.
•This contrasts with observations on chloroquine, where a similar lack of stereoselectivity in vitro is accompanied by a 10-fold loss of activity against the resistant strain.
The '265 patent discusses the unusual stereoselectivity of the biological properties as between the dextrorotatory and the levorotatory enantiomers.
Believing that there was no advantage to separation of the enantiomers of thienopyridines, and no other racemates were separated until November 1985 when Sanofi then determined the biological properties of the enantiomers of PCR 4099, and found that they had the rare characteristic of "absolute stereoselectivity": the dextrorotatory enantiomer provided all of the favorable antiplatelet activity but with no significant neurotoxicity, while the levorotatory enantiomer produced no antiplatelet activity but virtually all of the neurotoxicity.
42, S225-S227, (1991) • Both enantiomers of quinacrine and the racemic form of the drug showed equal activity in vitro against chloroquine-sensitive and - resistant strains of Plasmodium falciparum, without detectable stereoselectivity.
 S cholesterol + NADPH + O2 < 1-4 > (hydroxylation of cholesterol with strict regio - and stereoselectivity, inert towards other sterols and inter - mediates in conversion of cholesterol to bile acids ) (Reversibility:?
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