Definitions

from The American Heritage® Dictionary of the English Language, 4th Edition

  • n. Any of a group of enzymes that catalyze the hydrolysis of sulfate esters and are found in animal tissues and bacteria.

from Wiktionary, Creative Commons Attribution/Share-Alike License

  • n. Any of several enzymes, in animals and bacteria, which catalyze the hydrolysis of organic sulfates.

Etymologies

sulfat(e) + -ase.
(American Heritage® Dictionary of the English Language, Fourth Edition)

Examples

  • More information: "A canine Arylsulfatase G (ARSG) mutation leading to a sulfatase deficiency is associated with neuronal ceroid lipofuscinosis", Published: Aug. 17, 2010, in

    PhysOrg.com - latest science and technology news stories

  • "A canine Arylsulfatase G (ARSG) mutation leading to a sulfatase deficiency is associated with neuronal ceroid lipofuscinosis"

    innovations-report

  • In transfected cells or leukocytes from affected dogs, the missense change leads to a 75% decrease in sulfatase activity, providing a functional confirmation that the variant might be the NCL-causing mutation.

    innovations-report

  • Our results uncover a protein involved in neuronal homeostasis, identify a family of candidate genes to be screened in patients with Kufs 'disease, and suggest that a deficiency in sulfatase is part of the NCL pathogenesis.

    innovations-report

  • -- On November 25, 2009 - Ipsen announced the initiation of an international, multi-center, controlled, randomized Phase II clinical trial to evaluate the safety and efficacy of BN83495, its investigational first-in-class steroid sulfatase (STS) inhibitor, in advanced endometrial cancer.

    StreetInsider.com News Articles

  • -- On December 14, 2009 - Ipsen announced the preliminary results of a phase I trial in metastatic breast cancer with BN83495, Ipsen's lead and first-in-class orally available irreversible steroid sulfatase (STS) inhibitor.

    StreetInsider.com News Articles

  • His preliminary work laid the foundation for the eventual solution of the structure of estrone sulfatase.

    YubaNet.com

  • The aromatase and sulfatase projects were started at HWI by Dr. Yoshio Osawa more than 30 years ago.

    YubaNet.com

  • The other two enzyme structures determined by the Ghosh lab as part of this project were estrone sulfatase (2003) and 17beta-hydroxysteroid dehydrogenase type 1 (1996).

    YubaNet.com

  • Ipsen (Paris: IPN) today announced the initiation of an international, multi-center, controlled, randomized Phase II clinical trial to evaluate the safety and efficacy of BN83495, its investigational first-in-class steroid sulfatase (STS) inhibitor, in advanced endometrial cancer.

    THE MEDICAL NEWS

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