American Heritage® Dictionary of the English Language, Fourth Edition
- n. The final stage of syphilis, following a latent period that may last years, characterized by spread of the disease to many organs and tissues, including the skin, bones, joints, heart, brain, and spinal cord.
GNU Webster's 1913
- adj. (Med.) the third and last stage of syphilis, in which it invades the bones and internal organs.
- n. the third stage; characterized by involvement of internal organs especially the brain and spinal cord as well as the heart and liver
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