Definitions
from Wiktionary, Creative Commons Attribution/Share-Alike License.
- verb Present participle of
transactivate . - adjective That
stimulates a host cell bytransactivation
Etymologies
Sorry, no etymologies found.
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Examples
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N-term β-catenin (1-567 aa), and SATB1 or empty vector in indicated combinations. β-catenin proteins encoded by both these constructs can translocate into nucleus and are therefore capable of transactivating Wnt/TCF/β-catenin targets; however, the N-term (1-576) protein does not interact with SATB1.
PLoS Biology: New Articles Dimple Notani et al. 2010
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The objective of this study was to quantify the nuclear localization and DNA binding activity of p65, the major transactivating nuclear factor-kappa B (NF-kappaB) subunit, in full-thickness fetal membranes (FM) and myometrium in the absence or presence of term or preterm labor.
BioMed Central - Latest articles Sonali Vora 2010
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Because of the presence of two promoters, p63 encodes two major classes of proteins: those containing a transactivating (TA) domain homologous to the one present in p53 (i.e. TAp63), and those that lack the TA domain (i.e. ΔNp63) [1], [2].
PLoS ONE Alerts: New Articles Venkata Sabbisetti et al. 2009
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Through this mechanism, PKR can modulate transcription, as revealed by its ability to prevent the capacity of RHA to catalyze transactivating response
MicrobiologyBytes 2009
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Yang A, Kaghad M, Wang Y, Gillett E, Fleming MD, et al. (1998) p63, a p53 homolog at 3q27-29, encodes multiple products with transactivating, death-inducing, and dominant-negative activities.
PLoS ONE Alerts: New Articles Venkata Sabbisetti et al. 2009
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Hinchliffe S, Sommer MH, Zerboni L, et al. (2003) Mutational analysis of open reading frames 62 and 71, encoding the varicella-zoster virus immediate-early transactivating protein, IE62, and effects on replication in vitro and in skin xenografts in the SCID-hu mouse in vivo.
PLoS ONE Alerts: New Articles Felix Wussow et al. 2009
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The AF2 domain recruits cofactors necessary for NR5A1 transactivating activity.
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The AF2 domain recruits cofactors necessary for NR5A1 transactivating activity.
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The AF2 domain recruits cofactors necessary for NR5A1 transactivating activity.
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The transactivating module of NFAT5 switches its function from an stimulus-specific activator of transcription in interphase to an stimulus-independent repressor of binding to DNA in mitosis.
PLoS ONE Alerts: New Articles Anaïs Estrada-Gelonch et al. 2009
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