Definitions
from Wiktionary, Creative Commons Attribution/Share-Alike License.
- noun A
protein found in human blood; specifically, a serum and cerebrospinal fluid carrier of the thyroid hormone thyroxine.
Etymologies
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Examples
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Four of the peaks that were discovered have been identified as transthyretin, apolipoprotein A1, apolipoprotein C1 and cystatin C.
BioMed Central - Latest articles Anne Julie Overgaard 2010
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In the case of TTR amyloid polyneuropathy, a protein called transthyretin (TTR) "misfolds" and amyloid fibrils cluster in peripheral nerve tissues that serve limbs and organs.
PhysOrg.com - latest science and technology news stories 2009
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Cell Phone Use Linked to Brain Changes - Study finds an association between cell phone use and an increased amount of a protein called transthyretin in the blood.
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The drug treats a progressively fatal neurodegenerative condition, transthyretin familial amyloid polyneuropathy, that is currently treated by liver transplant.
Pfizer Sells Capsugel Unit to KKR for $2.38 Billion Jonathan D. Rockoff 2011
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European research over the last 20 years has clearly identified immune-system effects due to Agent Orange's poisoning of transthyretin, the protein that moves thyroid and vitamin A hormones around the body and controls modulation of the immune system.
MAIL CALL 2007
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The protein, known as “transthyretin,” protects brain cells from gradual deterioration by blocking another toxic protein that contributes to the disease process.
"Brain Protein That Halts Progression Of Alzheimer’s" M-mv 2004
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The protein, known as “transthyretin,” protects brain cells from gradual deterioration by blocking another toxic protein that contributes to the disease process.
Archive 2004-10-01 M-mv 2004
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Indeed, we believe that RNAi therapeutics targeting transthyretin could represent a major advance for the treatment of ATTR - a significant unmet medical need where breakthrough therapies are needed, said Saraswathy Nochur, Ph.
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These include ALN-TTR for the treatment of transthyretin-mediated amyloidosis ATTR, ALN-PCS for the treatment of severe hypercholesterolemia, ALN-HPN for the treatment of refractory anemia, and two additional programs from the company's ongoing discovery efforts that will be advanced into development later in 2011.
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ALN-TTR01 is a systemically delivered RNAi therapeutic being developed for the treatment of transthyretin (TTR)-mediated amyloidosis (ATTR), including familial amyloidotic polyneuropathy
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