from The Century Dictionary and Cyclopedia
- In cytology and pathology, having three nuclei: said of certain cells and abnormal eggs.
from WordNet 3.0 Copyright 2006 by Princeton University. All rights reserved.
- adj. having three nuclei
Sorry, no etymologies found.
The intracellular domain is not required for the formation of bi/trinucleate precursors, in a fraction of hemisegments examined.
Previous studies have shown that Rolling pebbles (Rols)/Antisocial (Ants), a scaffold protein with multiple protein interaction domains, is involved in sustaining fusion beyond the bi/trinucleate precursor stage.
ΔCT4-flag is able to rescue the duf, rst mutant up to the bi/trinucleate stage
Initial fusion gives rise to a bi/trinucleate precursor followed by more fusion cycles forming a mature muscle.
Fusion completely fails in a duf, rst mutant, and is blocked at the bi/trinucleate stage in rols and loner single mutants.
It is possible that even in the absence of robust Duf dependent signal transduction, requirements for the formation of a bi/trinucleate precursor are met.
The first round of fusion leads to the formation of a bi/trinucleate precursor and requires molecules like Duf and Rst while later rounds of fusion require molecules like Rols, functions predicted by the phenotype of these mutants
Events are repeated in a stepwise manner first leading to the formation of a bi/trinucleate precursor, followed by more such rounds of fusion, accompanied by growth at the ends of the myotube.
Fusion efficiency is significantly compromised in the double mutants compared to the single mutants (Students t-test P doi: 10.1371/journal. pone.0009374.g006 rols and loner single mutants block fusion at the bi/trinucleate stage with an average nuclear number of 2. 89±0.91 and 2. 11±0.91 respectively (
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