from Wiktionary, Creative Commons Attribution/Share-Alike License
- n. The reaction of a substance with acetic acid or one of its derivatives; the introduction of one or more acetyl groups into a substance
from The Century Dictionary and Cyclopedia
- n. The treatment of organic substances with acetic anhydrid in order to determine the presence and amount of alcoholic hydroxyl. Same as acetylization.
from WordNet 3.0 Copyright 2006 by Princeton University. All rights reserved.
- n. the process of introducing an acetyl group into a compound
Sorry, no etymologies found.
Histones are modified in various ways, including through a process called acetylation, which in turn modifies chromatin shape and structure.
"Many mitochondrial proteins undergo a small chemical modification known as acetylation, which varies during feeding and fasting conditions," said Eric Verdin, MD, senior investigator and senior author of the study.
The second change, which is called acetylation, converts the CoA form of B5 back into acteyl CoA.
Studies of mutant huntingtin by MGH-MIND researchers and their collaborators suggested a possible connection with a process of protein modification called acetylation, in which enzymes add a molecule called an acetyl group to the amino acid lysine.
Many of these, such as acetylation, are fairly run of the mill.
Other post-translational modifications of HIF-1α, such as acetylation, phosphorylation and nitrosylation, were also reported, despite contradictory results with regard to their effect on HIF-1α protein stability and transcriptional activity
It's becoming increasingly evident, Hunter says, that the epigenetic changes like the methyl marks he observed and others, such as acetylation and phosphorylation, could play a significant role in the brain's response to stress and the treatment of stress related diseases, such as post-traumatic stress disorder.
In this regard, SUMO has been shown to act as antagonist of ubiquitination and have a role in the negative regulation of transcription, hence, sumoylation might block alternative lysine-targeted modifications such as acetylation or ubiquitination
Eric Verdin, senior investigator and senior author of the study, said: "Many mitochondrial proteins undergo a small chemical modification known as acetylation, which varies during feeding and fasting conditions.
Inhibiting deacetylation with HDAC inhibitors leads to increased acetylation.