Definitions
from The American Heritage® Dictionary of the English Language, 5th Edition.
- adjective Of or involving a change in the shape and activity of an enzyme that results from molecular binding with a regulatory substance at a site other than the enzymatically active one.
from Wiktionary, Creative Commons Attribution/Share-Alike License.
- adjective biochemistry, of an enzyme That
binds a compound on an inactive site and thus changesconformation in order to become eitheractive orinactive
Etymologies
from Wiktionary, Creative Commons Attribution/Share-Alike License
Support
Help support Wordnik (and make this page ad-free) by adopting the word allosteric.
Examples
-
Under the agreement, Addex will regain rights to intellectual property and know-how and can pursue the program independently. www.addexpharma.com discovers and develops an emerging class of small molecule drugs, called allosteric modulators, which have the potential to be more specific and confer significant therapeutic advantages over conventional "orthosteric" small molecule or biological drugs.
-
In contrast to some of its rivals, Addex has a relatively wide portfolio of new products and a novel technology platform known as allosteric modulation, factors which analysts say make it a potential star of the Swiss biotech sector.
Reuters: Top News 2009
-
In contrast to some of its rivals, Addex has a relatively wide portfolio of new products and a novel technology platform known as allosteric modulation, factors which analysts say make it a potential star of the Swiss biotech sector.
unknown title 2009
-
In contrast to some of its rivals, Addex has a relatively wide portfolio of new products and a novel technology platform known as allosteric modulation, factors which analysts say make it a potential star of the Swiss biotech sector.
Reuters: Top News 2009
-
The researchers have discovered that apamin binds away from the channel pore, and causes the shape of the channel to change through an 'allosteric' mechanism, resulting in block.
PhysOrg.com - latest science and technology news stories 2010
-
As an essential feature, interactions among the components of a system have effects (technically 'allosteric' effects) that help organize and coordinate its processes, allowing the self-replication to proceed.
Citizendium, the Citizens' Compendium - Recent changes [en] 2010
-
As an essential feature, interactions among the components of a system have effects (technically 'allosteric' effects) that help organize and coordinate its processes, allowing the self-replication to proceed.
Citizendium, the Citizens' Compendium - Recent changes [en] 2009
-
From these measurements we calculated all of the equilibrium constants of the "allosteric" cycle as follows: diliganded gating, unliganded gating, dissociation from the C (losed) conformation, and dissociation from the O (pen) conformation.
Journal of Biological Chemistry current issue P. A. Bafna 2009
-
Scientists already know that a family of 'allosteric' drugs can switch off this enzyme but until now no-one knew how they worked.
-
Most genetic control mechanisms are based on an "allosteric" molecule that both senses the problem and acts in response to the information.
Comments
Log in or sign up to get involved in the conversation. It's quick and easy.