from The American Heritage® Dictionary of the English Language, 4th Edition

  • adj. Of or relating to a nucleotide sequence that is complementary to a sequence of messenger RNA. When antisense DNA or RNA is added to a cell, it binds to a specific messenger RNA molecule and inactivates it.

from Wiktionary, Creative Commons Attribution/Share-Alike License

  • n. A molecule which interacts with a complementary strand of nucleic acids, so as to suppress its transcription.


anti- +‎ sense (Wiktionary)


  • The researchers also suppressed CPE-delta N in mice using an experimental approach called antisense and found tumors implanted into the animals did not spread.

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  • Isis Pharmaceuticals, Inc. engages in the discovery and development of a new class of drugs called antisense drugs using antisense technology, a novel drug discovery platform to generate News Articles

  • Working with a class of compounds known as antisense phosphorodiamidate morpholino oligomers, or PMOs, scientists conducted studies in which nine rhesus monkeys were challenged with lethal Ebola virus, reports

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  • Working with a class of compounds known as antisense phosphorodiamidate morpholino oligomers, or PMOs, scientists first performed a series of studies with mouse and guinea pig models of Ebola to screen various chemical variations. - latest science and technology news stories

  • Simard's team blocked this gene in mice and rats using gene-blocking therapy called antisense and showed that after a spinal cord injury, the damage and effects were much less without ABCC8.

  • Researchers demonstrate efficacy of antisense therapy for spinal muscular atrophy disease spinal muscular atrophy (SMA) might soon be treated with tiny, chemically modified pieces of RNA called antisense oligonucleotides (ASOs). - Articles related to Length of biological marker linked to cancer

  • In the study, Simard and his colleagues gave a drug called antisense oligodeoxynucleotide

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  • Unlike traditional gene therapy, which attempts to replace a mutated gene with a functional copy, exon skipping relies on a variation of a technique called antisense, in which short synthetic DNA or RNA molecules are designed to bind to a region of DNA or RNA and block its function.

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  • DIG-labelled antisense RNA probes synthesis, samples fixation and in situ hybridisation were carried out as previously described

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  • If a gene is read forwards - called 'sense' transcription - the protein is generated in the normal way, but if the other, complementary strand is transcribed - called antisense - no protein is made.



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