from The American Heritage® Dictionary of the English Language, 4th Edition

  • adj. Having an affinity for, tending to combine with, or capable of dissolving in lipids.

from Wiktionary, Creative Commons Attribution/Share-Alike License

  • adj. Having the quality of dissolving in lipids
  • adj. Typically have the quality of being composed of mostly nonpolar bonds

from the GNU version of the Collaborative International Dictionary of English

  • adj. having an affinity for lipids; -- of chemical substances or parts of molecules. Contrasted to lipophobic or polar.

from WordNet 3.0 Copyright 2006 by Princeton University. All rights reserved.

  • adj. having an affinity for lipids


from Wiktionary, Creative Commons Attribution/Share-Alike License

lipo- (“lipid”) + -philic (“loving”)


  • They are often referred to as lipophilic or fat-loving chemicals.

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  • The most common type of statins, known as lipophilic, had the greatest impact.

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  • Plus, mercury is lipophilic, meaning that it concentrates in fatty tissues, especially in the brain, which is made mostly of fat.

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  • Air and ocean currents carry pesticides from industrial zones to the Arctic, where the "lipophilic" (fat-loving) substances accumulate in fatty tissues.

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  • Many of them are lipophilic -- meaning they cling to fat.

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  • An ingredient has to be watery but moderately lipophilic too.

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  • Applying a lipophilic or aquaphilic product onto a dried-out surface is like putting a cream or lotion on a stone—it just sits there or slides off because there are no pathways in which to move deeper.

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  • Theoretically, lipophilic, or fatty, molecules can penetrate fat easily—taking an intercellular approach meaning that they move in between the cells through the fatty lipids mortar.

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  • Fatty ceramides are “lipophilic,” allowing oil and fat substances to enter.

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  • The addition of a fat molecule, for example, could make a watery ingredient just lipophilic enough to pass through the cell membrane and move on to the dermis.

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