from Wiktionary, Creative Commons Attribution/Share-Alike License
- n. The presence of abnormally small eyes
from the GNU version of the Collaborative International Dictionary of English
- n. An unnatural smallness of the eyes, occurring as the result of disease or of imperfect development.
from The Century Dictionary and Cyclopedia
- n. An abnormal smallness of the eye. Also microphthalmy.
Sorry, no etymologies found.
A major clinical and laboratory effort is ongoing in clinical and genetic aspects of congenital anophthalmia/microphthalmia.
Ongoing neuroradiology projects include orbital volumetric analysis of microphthalmia, orbital holography and functional MRI eyelid and orbital structures using special surface coils.
According to the Centers for Disease Control and Prevention, these eye defects, called anophthalmia and microphthalmia, occur in one out of 5,300 births in the U.S. About one out of 10,000 babies are born with amniotic band syndrome.
Carreira S, Liu B, Goding CR (2000) The gene encoding the T-box factor Tbx2 is a target for the microphthalmia-associated transcription factor in melanocytes.
Hanniford D, Menendez S, Reavie L, Zou X, et al. (2009) Aberrant miR-182 expression promotes melanoma metastasis by repressing FOXO3 and microphthalmia-associated transcription factor.
The microphthalmia transcription factor (MITF) contains two N-terminal domains required for transactivation of osteoclast target promoters and rescue of mi mutant osteoclasts by K.C. Mansky, G. Purdom, et al. Journal of Leukocyte Biology
The microphthalmia transcription factor and the related helix-loop-helix zipper factors TFE-3 and TFE-C.collaborate to activate the tartrate-resistant acid phosphatase promoter by K.C. Mansky, G. Purdom, et al. Journal of Leukocyte Biology