Definitions

from Wiktionary, Creative Commons Attribution/Share-Alike License

  • adj. Having a similar structure indicating divergence from a common ancestral gene
  • adj. Having a similar structure, quality or nature indicating divergence or relationship from a common point of origin.

Etymologies

Sorry, no etymologies found.

Examples

  • Phylogenitic analysis, homologus/paralogous gene structure/functional relationships are predicated on these simple evolutionary concepts and undergird breakthroughs in understanding mechanisms and pathways of the cell necessary for modern medicine.

    Egnorance: The Egotistical Combination of Ignorance and Arrogance - The Panda's Thumb

  • Conversely, the reason for the increase in dN/dS in many genes within CNV regions could be attributed to their higher number of paralogous sequences.

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  • The downstream paralogous Ugt5b5p pseudogene does not share any

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  • Mammals have three Ugt2a and multiple Ugt2b genes genes have orthologs in mice and rats, while the human UGT2B genes display paralogous relationship to those of mouse and rat

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  • The subunit, a 400 kDa polypeptide, is a concatenation of eight paralogous functional units.

    BioMed Central - Latest articles

  • Vatolin S, Abdullaev Z, Pack SD, Flanagan PT, Custer M, et al. (2005) Conditional expression of the CTCF-paralogous transcriptional factor BORIS in normal cells results in demethylation and derepression of MAGE-A1 and reactivation of other cancer-testis genes.

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  • D. discoideum CbfA-like protein, CbfB, share a paralogous domain arrangement that includes the JmjC domain, presumably a chromatin-remodeling activity, and two zinc finger-like

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  • D. discoideum CbfA and CbfB are paralogous within the JmjC / ZF region, but have completely unrelated carboxy-terminal domains.

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  • Exonuclease III - another example of paralogous proteins with conserved attenuation pattern among the species.

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  • Bonilla JA, Moura PA, Bonilla TD, Yowell CA, Fidock DA, et al. (2007) Effects on growth, hemoglobin metabolism and paralogous gene expression resulting from disruption of genes encoding the digestive vacuole plasmepsins of Plasmodium falciparum.

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