from The American Heritage® Dictionary of the English Language, 4th Edition

  • n. See flatworm.

from Wiktionary, Creative Commons Attribution/Share-Alike License

  • n. Any flatworm of the phylum Platyhelminthes

from The Century Dictionary and Cyclopedia

  • n. [⟨ NL. Platyhelmintha.] A member of the Platyhelmintha, in any sense; a flatworm, as a cestoid, trematoid, turbellarian, or nemertean.

from WordNet 3.0 Copyright 2006 by Princeton University. All rights reserved.

  • n. parasitic or free-living worms having a flattened body


From New Latin Platyhelminthēs, phylum name : platy- + Greek helmīs, helminth-, parasitic worm; see wel-2 in Indo-European roots.
(American Heritage® Dictionary of the English Language, Fourth Edition)


  • In contrast to their mammalian hosts, platyhelminth (flatworm) parasites studied so far, lack conventional thioredoxin and glutathione systems.

    BioMed Central - Latest articles

  • In contrast, the free-living platyhelminth Schmidtea mediterranea (Class Turbellaria) possesses conventional and linked thioredoxin and glutathione systems.

    BioMed Central - Latest articles

  • We examine platyhelminth genomes and transcriptomes and find that all platyhelminth parasites (from classes Cestoda and Trematoda) conform to a biochemical scenario involving, exclusively, a selenium-dependent linked thioredoxin-glutathione system having TGR as a central redox hub.

    BioMed Central - Latest articles

  • We also provide experimental evidence that alternative initiation of transcription and alternative transcript processing contribute to the generation of TGR variants in platyhelminth parasites.

    BioMed Central - Latest articles

  • TGR has been recently validated as a drug target for schistosomiasis and new drug leads targeting TGR have recently been identified for these platyhelminth infections that affect more than 200 million people and for which a single drug is currently available.

    BioMed Central - Latest articles

  • Little is known regarding the genomic structure of flatworm TGRs, the expression of TGR variants and whether the absence of conventional thioredoxin and glutathione systems is a signature of the entire platyhelminth phylum.

    BioMed Central - Latest articles

  • Platyhelminth parasites possess a unique and simplified redox system for diverse essential processes, and thus TGR is an excellent drug target for platyhelminth infections.

    BioMed Central - Latest articles

  • Schistosoma mansoni (a platyhelminth) [17] Phylogenetic comparisons of putative Hirudo innate immune response genes present within the Hirudo transcriptome database herein described show a strong resemblance to the corresponding mammalian genes, indicating that this important physiological response may have older origins than what has been previously proposed.

    BioMed Central - Latest articles

  • Mushroom bodies are prominent neuropils involved in the processing of multiple sensory inputs as well as associative learning in the insect, platyhelminth, and annelid brains.

    BioMed Central - Latest articles


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