from The American Heritage® Dictionary of the English Language, 4th Edition

  • n. A proteinase of high specificity that is released by the kidney and acts to raise blood pressure by activating angiotensin.

from Wiktionary, Creative Commons Attribution/Share-Alike License

  • n. An circulating enzyme released by mammalian kidneys that converts angiotensinogen to angiotensin-I. Because its activity ultimately leads to formation of angiotensin-II and aldosterone, this hormone plays a role in maintaining blood pressure.

from WordNet 3.0 Copyright 2006 by Princeton University. All rights reserved.

  • n. a proteolytic enzyme secreted by the kidneys; catalyzes the formation of angiotensin and thus affects blood pressure


from The American Heritage® Dictionary of the English Language, 4th Edition

Latin rēnēs, kidneys + -in.


  • What happens is the kidneys in some ways, John, get overloaded and as a result of having all of that excess salt they start to release these hormones called renin, r-e-n-i-n, and what that causes is a shrinking of the blood vessels.

    CNN Transcript May 12, 2009

  • Drugs that block a hormonal cascade, known as the renin-angiotensin-aldosterone system


  • The discovery provides insight into a protein, renin, that is important in blood pressure regulation ...


  • "We are focusing on this system because we already know that inhibiting and controlling the production of renin, which is an enzyme that plays a role in the renin-angiotensin-aldosterone system, helps to preserve kidney function," Pool said.

    Baylor College of Medicine News

  • Don't expect a routine test for that hormone, called renin, any time soon.

    Dallas / Fort Worth news, weather, sports, traffic and video from

  • Future studies are needed to evaluate the effect of prophylactic treatment with nonanticoagulant medication such as renin-angiotensin-system inhibitors, they add.

  • ALIOF. PK) announced today that it has discontinued the development in partnership with MRK of an early stage compound (classified as a renin inhibitor) for the treatment of high blood pressure due to poor results from several clinical trials.

    Healthcare Sector and Stocks Analysis from Seeking Alpha

  • Salt sensitivity in obese individuals may be a consequence of increased sympathetic activity, decreased responsiveness to atrial natriuretic peptide, activation of the renin-angiotensin system or mechanical pressure on the kidneys that increases sodium reabsorption.

    Dr. Sharma’s Obesity Notes » Blog Archive » And the 2009 “Salt Lick” Award goes to Pizza!

  • The third study, by a team led by Dr. Alderman, found that when an anti-renin drug was used in certain patients with low renin levels, it had the undesirable effect of increasing blood pressure.

    Getting the Right Hypertension Drug

  • It found that renin levels could also serve as a guide for prescribing add-on therapies for some patients.

    Getting the Right Hypertension Drug


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