Definitions

from Wiktionary, Creative Commons Attribution/Share-Alike License

  • n. An organic compound formed from four amino acids joined by peptide bonds.

Etymologies

from Wiktionary, Creative Commons Attribution/Share-Alike License

tetra- +‎ peptide.

Examples

  • The other antiserum was prepared by immunization of a rabbit (Rabbit B) with the COOH-terminal gastrin tetrapeptide amide.

    Nobel Lecture Radioimmunoassay: A Probe For Fine Structure Of Biologic Systems

  • To exclude the possibility that the observed effects of salubrinal were specific for the tetrapeptide aldehyde inhibitor PSI only, two other inhibitors, MG132 and bortezomib, were also evaluated.

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  • Vanhoorelbeke K, Depraetere H, Romijn RA, Huizinga EG, De Maeyer M, et al. (2003) A consensus tetrapeptide selected by phage display adopts the conformation of a dominant discontinuous epitope of a monoclonal anti-VWF antibody that inhibits the von Willebrand factor-collagen interaction.

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  • To better characterize falcipain activities and determine whether a clear pathway of hemoglobin degradation by falcipains is present, activities were studied by three assays, evaluating action against a tetrapeptide library, 12-mer peptides representing the sequences of α and β globin, and intact hemoglobin.

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  • In each library, each tetrapeptide had a fixed amino acid at one position (P 1, P2, P3, or P4) and randomized amino acids at the other positions

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  • Thus, although of limited utility in discriminating activity against native protein substrates, the elaboration of enzyme specificity using tetrapeptide scanning libraries provided accurate prediction of optimal small molecule inhibitors.

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  • P Cleavage preferences of falcipain-2 and falcipain-3 against a tetrapeptide library.

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  • It is a pure synthetic tetrapeptide developed to decrease nerve stimulation, which Cognis says helps to increase skin tolerance.

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