from The American Heritage® Dictionary of the English Language, 4th Edition
- n. Any of various natural or synthetic compounds containing two or more amino acids linked by the carboxyl group of one amino acid to the amino group of another.
from Wiktionary, Creative Commons Attribution/Share-Alike License
- n. A class of organic compounds consisting of various numbers of amino acids in which the amine of one is reacted with the carboxylic acid of the next to form an amide bond.
- n. The peptide bond itself.
from WordNet 3.0 Copyright 2006 by Princeton University. All rights reserved.
- n. amide combining the amino group of one amino acid with the carboxyl group of another; usually obtained by partial hydrolysis of protein
The word peptide is derived from a Greek term meaning ‘small digestibles’; a peptide also forms a type of chain, or bond.
They stand for corresponding amino acids in peptide chains.
Their work exploits the way certain peptide sequences can be made to self-assemble into mesh-like sheets of "nanofibres" when immersed in salt solutions.
We learnt that the basic biochemical principles, such as generation of high-energy intermediates involved in peptide bond formation, were preserved along evolution regardless of whether the bond is encoded genetically or not, or whether it links two amino acids, or two proteins, or an amino acid to the elongoting polypeptide chain.
The signal peptide is finally cleaved and the protein is secreted out of the cell.
The growing protein chain penetrates the channel, the signal peptide is cleaved, and the completed protein is released into the lumen of the endoplasmic reticulum.
First, a signal peptide is formed as a part of the protein.
Only certain peptide antigens will fit each of the HLA subtypes.
Merrifield's methodology has brought about a revolution in peptide and protein chemistry and thousands of different peptides have now been synthesized using this approach.
In 2004 Hynda Kleinman and her colleagues at the National Institutes of Health discovered that this molecule, called a peptide, blocks the metastasis of melanoma to the lungs and other organs, at least in lab animals.