“A simplified diagnostic panel of CA19-9, ApoC-I and ApoA-II improves the diagnostic ability of CA19-9 alone and may have clinical utility.”
“A seven-protein panel from the training set PC vs DC and from PC vs HV samples gave the ROC area under the curve (AUC) of 0.90 and 0.90 compared with 0.87 and 0.91 for CA19-9.”
“CA19-9 levels are associated with lymph node metastases, but inversely with cirrhosis.”
“Their research demonstrated that hepatitis B infection, carbohydrate antigen 19-9 (CA19-9), carcinoembryonic antigen (CEA), and a-fetoprotein (AFP) are associated with ICC development.”
“Their research demonstrated that carbohydrate antigen 19-9 (CA19-9), carcinoembryonic antigen (CEA), and a-fetoprotein (AFP) are associated with ICC development.”
“Also, identifying biomarkers with better sensitivity and specificity than CA19-9 will significantly improve the diagnosis of pancreatic cancer.”
“In fact, recent reports have shown that CEACAM1 and MUC1 indeed possess higher sensitivity and specificity for diagnosis of PDACs than CA19-9, the current gold standard It is becoming clear that the tumor microenvironment is involved in initiation, proliferation, migration, invasion, angiogenesis, and metastasis of cancers.”
“Pancreatic cancer is a deadly disease for which the available biomarkers, such as CA19-9, lack the desired sensitivity and specificity for early detection”
“The lowest CA19-9 levels during treatment with gemcitabine were also recorded.”
“Laboratory data (Hematocrit, hemoglobin, glucose, LDH, renal and liver function and CA19-9);”
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