antigen

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Dacetuzumab is a humanized monoclonal antibody that targets the CD40 antigen, which is expressed on most B lineage hematologic malignancies, as well as some solid tumors.

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Definitions (2)

Toggle American Heritage definitions American Heritage Dictionary (1)

  1. noun A substance that when introduced into the body stimulates the production of an antibody. Antigens include toxins, bacteria, foreign blood cells, and the cells of transplanted organs.

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Toggle GNU Webster definitions GNU Webster's 1913

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Examples (37)

  • At Scripps Research Institute, for instance, the antigen is snipped off the deadly cholera pathogen. —  Omni: September 1994
  • Named CIMAVAX EGF, the antigen has been shown to be effective, extending patients 'survival and quality of life, said ... —  axisoflogic.com
  • Hepatitis B surface antigen, anti-hepatitis B core antigen IgM, anti-hepatitis C virus antibodies, anticytomegalovirus —  Health News from Medical News Today
  • In this regard, prostate stem cell antigen is a good example because although it is being tested as a therapeutic target for the treatment of prostate cancer, it is also overexpressed in pancreatic cancer Tables A-G. —  PLoS Medicine: New Articles
  • The analysis of thymic development in the transgenic TSCOT mice shows an absence of immature preselection thymocytes in the presence of self-antigen, a phenotype seen in other TCR transgenic systems in which the TCR is expressed inappropriately early. —  PLoS Biology: New Articles
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