from The American Heritage® Dictionary of the English Language, 4th Edition
- n. Any of various enzymes that catalyze the transfer of a phosphate group from a donor, such as ADP or ATP, to an acceptor.
from Wiktionary, Creative Commons Attribution/Share-Alike License
- n. Any of a group of enzymes that transfers phosphate groups from high-energy donor molecules, such as ATP, to specific target molecules (substrates); the process is termed phosphorylation.
from the GNU version of the Collaborative International Dictionary of English
- n. One of a class of enzymes that catalyze transfer of a phosphate group from ATP to another molecule; it is a type of phosphorylase.
from The Century Dictionary and Cyclopedia
- n. A ferment-like body which is capable of rendering physiologically active another ferment and thus produces chemical changes in a third body while in itself it is apparently inert.
from WordNet 3.0 Copyright 2006 by Princeton University. All rights reserved.
- n. an enzyme that catalyzes the conversion of a proenzyme to an active enzyme
Not always necessarily at the same time, but at least to be able to look at protein kinase activity, redox state, gene transcription, protein degradation, localization of DNAs and RNAs by slightly more indirect means, which if you use GFP and RFP to label a protein that in turn binds specifically to your favourite nucleic acid, and the list goes on and on.
This enzyme, called protein kinase G (PKG), is turned on and activated in response to injury or inflammation.
These included Viesturs Simanis, Sergio Moreno and Kathy Gould, who between them worked out that cdc2 encoded a protein kinase that was regulated during the cell cycle and was controlled by tyrosine phosphorylation.
The stronger stimulus will give rise to increased levels of the messenger molecule cAMP and thereby protein kinase A.
These messengers travel into the cell and activate a protein kinase, which starts to bind phosphate groups to other proteins, in this way altering their function.
This was eventually solved with the finding of the cyclic AMP-dependent protein kinase by one of my postdoctoral fellows, Donal A. Walsh.
The fact that cyclic AMP mediates its effects via stimulation of a protein kinase activating the enzyme phosphorylase explains how a hormone signal can lead to quick mobilization of sugar.
A protein kinase moves a phosphate group (P) from ATP (ADP (P)) to the protein.
In several instances an erroneously regulated protein kinase activity is responsible.
A protein kinase moves a phosphate group from ATP to the protein.
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