enzyme

• Understanding Top1 also is clinically important, because the enzyme is the target of anti-cancer drugs called camptothecins, which prevent Top1 from resealing the nicked DNA, keeping the replication machinery from working, and killing proliferating cancer cells.
• The results also show that the enzyme is able to effectively select for high affinity and specificity for the same chemical moieties both in the context of smaller substrates, and in that of a larger reactive intermediate. —  CiteULike: Everyone's library
• The enzyme, which is abundant only in fat tissue, is called adipose-specific phospholipase A2 —  Health News from Medical News Today
• "The observed dependence on GSK3," the researchers wrote, means the enzyme is a potential therapeutic target in MLL. —  MedPageToday.com - medical news plus CME for physicians
• They note that the enzyme could be administered as an injection, or as part of a feeding trial, either as part of natto or as purified nattokinase. —  NutraIngredients-USA RSS

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