American Heritage® Dictionary of the English Language, Fourth Edition
- n. An enzyme found primarily at nerve endings that catalyzes the hydrolysis of acetylcholine into acetic acid and choline.
- n. an enzyme that hydrolyses acetylcholine (into choline and acetic acid)
- cholin(e) + esterase. (American Heritage® Dictionary of the English Language, Fourth Edition)
“Fortunately, nerves contain an enzyme called cholinesterase (koh'lin-es'tur-ays) which brings about the breakup of acetylcholine to acetic acid and choline once more.”
“Tim Foley Alzheimer's disease is often treated by a class of drugs called cholinesterase inhibitors, which help boost levels of a brain chemical called acetylcholine.”
“The suspect compounds, known as cholinesterase inhibitors, aren't normally toxic at low levels.”
“Memantine is intended to treat moderate to severe Alzheimer's, but it is frequently used in mild Alzheimer's patients "off-label" - for uses other than those approved by the Federal Drug Administration - either alone or in combination with a drug known as a cholinesterase inhibitor.”
“In the study, it was found that DEET blocked the enzyme cholinesterase, which is essential for transmitting messages from the brain to the muscles, in experiments done on rodents using an amount of DEET equivalent to that used by humans.”
“A mainstay of treatment for Alzheimer's is a class of drugs called the cholinesterase inhibitors.”
“Currently, a class of drugs called cholinesterase inhibitors are widely used to treat Alzheimer's patients,”
“Compounds known as cholinesterase inhibitors (like the medication Donepezil, sold as Aricept) may stabilize early”
“Here's the source report: Deet inhibits cholinesterase: Evidence for inhibition of cholinesterases in insect and mammalian nervous systems by the insect repellent deet (BioMed Central)”
“A number of prescription drugs are available to fight Alzheimer's—including cholinesterase inhibitors that work to improve memory and thought but are not a cure.”
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