Definitions

from The American Heritage® Dictionary of the English Language, 4th Edition

  • n. Any of various enzymes, including the endopeptidases and exopeptidases, that catalyze the hydrolytic breakdown of proteins into peptides or amino acids.

from Wiktionary, Creative Commons Attribution/Share-Alike License

  • n. An enzyme that cuts or cleaves proteins.

from The Century Dictionary and Cyclopedia

  • n. A generic term for proteolytic ferments.

from WordNet 3.0 Copyright 2006 by Princeton University. All rights reserved.

  • n. any enzyme that catalyzes the splitting of proteins into smaller peptide fractions and amino acids by a process known as proteolysis

Etymologies

From prote(in) + -ase. (Wiktionary)

Examples

  • Both Incivek and Victrelis are known as protease inhibitors, designed to block an enzyme that helps the hepatitis C virus replicate.

    Hepatitis C Drug Approved

  • Both drugs are known as protease inhibitors, which are designed to block an enzyme that helps the hepatitis C virus replicate.

    Hepatitis C Drugs Await FDA Approval

  • Kidney beans also contain protease inhibitors which frustrate the development of cancerous cells.

    Archive 2006-09-01

  • Prezista, which has been on the market since 2006, is a so-called protease inhibitor designed to treat HIV infection and is taken with the drug Norvir, in combination with other antiretroviral agents.

    Gilead, J&J Agree to Develop New Combination HIV Drug

  • The FDA is expected to decide soon on telaprevir, another so-called protease inhibitor from Vertex Pharmaceuticals Inc. and Johnson & Johnson .

    FDA Clears Merck Hepatitis Drug

  • Both the Merck and Vertex drugs are known as protease inhibitors, which are designed to block an enzyme that helps hepatitis C virus replicate.

    Corporate Watch

  • Vertex and Schering-Plough are developing drugs called protease inhibitors, which fight viral replication.

    Firms Race for Hepatitis C Drugs

  • They belong to a barely tested class of AIDS medications called protease inhibitors, which attack the virus's capacity to replicate (page 68).

    The End Of Aids?

  • By combining new drugs called protease inhibitors with old workhorses like AZT, desperately ill patients are achieving miraculous remissions.

    Targeting A Deadly Scrap Of Genetic Code

  • Two research teams showed that when AZT and a related drug are combined with new agents called protease inhibitors, the effect on patients is breathtaking.

    New Aids Optimism

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