Definitions
Wiktionary
- n. biochemistry Any of several intracellular proteolytic enzymes that mediate apoptosis
WordNet 3.0
- n. any of a group of proteases that mediate apoptosis
Examples
“The study, published today in the Journal Nature, used mice that were genetically engineered with deadbeat cells that carry a molecule, called caspase 8.”
“Scientists exposed genetically engineered mice to a drug that activates a molecule called caspase 8 that kills senescent cells.”
“They found that the molecule called caspase, which was already well known for killing cells, could be used to target specific cancerous ones.”
“When they blocked or removed a key death-promoting protein called caspase 3, they found that stem cells stopped producing new muscle fibres.”
“They have discovered that the novel effect of caspase 3 in stem cells is related to its ability to activate another protein that cuts up the cell's DNA (called caspase-activated DNase) and has also traditionally been associated with programmed cell death.”
“In the new study, Xue and his team found that a well-known cellular molecule called caspase”
“In the cancer study, researchers identified a key sequence of amino acids-arginine, glycine, and aspartic acid, (the RGD motif) - that triggered the death of leukaemia cells by activating a protein called caspase-3.”
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“This protein, known as caspase 8, is deficient in humans with eczema, but produced in excess amounts by diabetics.”
“For example, it activates the enzyme caspase, which is involved in processes that lead to apoptosis (programmed cell death).”
“In the cancer study, de Mejia's group identified a key sequence of amino acids -- arginine, glycine, and aspartic acid, (the RGD motif) -- that triggered the death of leukemia cells by activating a protein called caspase-3.”
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