Definitions

from The American Heritage® Dictionary of the English Language, 4th Edition

  • n. An enzyme that catalyzes the hydrolysis of peptides into amino acids.

from Wiktionary, Creative Commons Attribution/Share-Alike License

  • n. Any enzyme that catalyzes the hydrolysis of peptides into amino acids; a protease

from WordNet 3.0 Copyright 2006 by Princeton University. All rights reserved.

  • n. any enzyme that catalyzes the splitting of proteins into smaller peptide fractions and amino acids by a process known as proteolysis

Etymologies

Sorry, no etymologies found.

Examples

  • CD26/dipeptidyl peptidase IV: A regulator of immune function and a potential molecular target for therapy.

    The UltraMind Solution

  • University, who worked at that time on translocation of proteins across the endoplasmic reticulum (ER) membrane, a process that involves cleavage of the leader peptide by signal peptidase, to Jeffrey Roberts in Cornell University who worked on E. coli RecA protein-directed cleavage of phage l repressor and its requirement for polynucleotide, and to Harvey Lodish at the M.I.T. who worked, among other subjects, on processing of viral polyproteins.

    Aaron Ciechanover - Autobiography

  • Recent comments by Dr. Daniel Drucker, a professor at the University of Toronto and leader in diabetes and endocrinology, suggested dipeptidyl peptidase agents such as those being developed by Merck and Novartis have potential as effective second-line treatments for type 2 diabetes, according to Morgan Stanley.

    Merck's Januvia Has 'Huge' Commercial Potential For Diabetes

  • It was not until the mid-1990s that researchers saw another way: An enzyme called dipeptidyl peptidase four DPP4 broke down GLP, and by inhibiting it, researchers could boost GLP levels in the body.

    Merck Starts Diabetes Race

  • Those results, as well as data on a class of drugs known as dipeptidyl peptidase IV inhibitors DPIV, could provide a catalyst for OSI shares, the Wachovia analyst said.

    OSI's Macugen Still Burdened By Lucentis Threat

  • Both pills work by inhibiting an enzyme called dipeptidyl peptidase 4 DPP-IV, which breaks down hormones that help control blood sugar.

    Merck, Novartis Square Off In Diabetes DuelDiabetes Duel

  • Some of the preexisting protein translocation apparatus of the endosymbiont appears to have been commandeered, including molecular chaperones, the signal peptidase, and some components of the protein-targeting machinery.

    3 recent reports use evolution to study mechanisms of antibody diversification - The Panda's Thumb

  • Osborne, who expects FDA approval of Novartis' Galvus in the first quarter, is one of a handful of analysts who believe Byetta will see significant competition from a new class of diabetes treatments known as dipeptidyl peptidase inhibitors.

    Amylin Gets Euro OK For Byetta, Shares Fall

  • A peptidase enzyme capable of acting on any peptide linkage in a peptide chain.

    Alcohol and The Addictive Brain

  • We also now have a library of dipeptidyl-peptidase IV DPP-4 inhibitors that we

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