pepsinogen

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The low pH also activates the enzyme precursor pepsinogen into the active enzyme pepsin by self-cleavage.

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Definitions (4)

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  1. noun The inactive precursor to pepsin, formed in cells of the mucous membrane of the stomach and converted to pepsin by autocatalysis in the presence of hydrochloric acid.

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Examples (6)

  • The low pH also activates the enzyme precursor pepsinogen into the active enzyme pepsin by self-cleavage. —  Original Signal - Transmitting Digg
  • When HCL is at a low, something that happens to most people as they age, then the other component in digesting proteins, pepsinogen wont work properly. —  Article Source
  • HCL stimulates pepsinogen to turn into pepsin, so it is a crucial part of the digesting proteins process. —  Article Source
  • H. pylori (Hp), as well as the levels of pepsinogen I (PGI). —  Naturejobs - All Jobs
  • We sought to 1) determine the incidence of pepsin / pepsinogen presence in the middle ear cleft of a large sample of pediatric patients undergoing myringotomy with tube placement for OM; 2) compare this with a control population of pediatric patients undergoing middle ear surgery (cochlear implantation) with no documented history of OM; 3) analyze potential risk factors for OM in children with EORD demonstrated by the presence of pepsin in the middle ear cleft; and 4) determine if pepsin positivity at the time of myringotomy with tube placement predisposes to posttympanostomy tube otorrhea. —  CiteULike: Everyone's library
 

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/pɛpˈsɪnədʒɛn/
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