Definitions
American Heritage® Dictionary of the English Language, Fourth Edition
- n. Any of several enzymes, such as endonucleases and exonucleases, that hydrolize nucleic acids.
Century Dictionary and Cyclopedia
- n. A ferment which can cause the cleavage of nucleins. Specifically
- n. One of several bacteriolytic ferments so-named on account of their ability to digest the nucleoproteids of the bacterial cells.
Wiktionary
- n. biochemistry Any of several enzymes capable of cleaving the phosphodiester bonds between the nucleotide subunits of nucleic acids.
WordNet 3.0
- n. general term for enzymes that catalyze the hydrolysis of nucleic acid by cleaving chains of nucleotides into smaller units
Examples
“The enzyme, which they named FAN1, appears to be a nuclease, which is capable of slicing through strands of DNA.”
“Support for a particulate substructure of chromatin came from electron microscopy and from nuclease digestion and sedimentation analysis.”
“It was also demonstrated that a ribonuclease III-like nuclease, called Dicer, is responsible for the processing of dsRNA to short RNA34.”
Advanced Information: The 2006 Nobel Prize in Physiology or Medicine
“An RNA-directed nuclease mediates post-transcriptional gene silencing in Drosophila cells.”
Advanced Information: The 2006 Nobel Prize in Physiology or Medicine
“Each finger binds to a specific combination of DNA bases and is attached to a DNA-cutting enzyme called a nuclease.”
“The micrococcal nuclease calcium dependence was put to good use by Hugh Pelham, a graduate student in the lab, who developed the use of nuclease treatment of the lysate to assay heterologous mRNAs.”
“One other thing I learned about during the studies on the inhibition of protein synthesis by dsRNA was that micrococcal nuclease, which requires Ca2+ for activity, did not inhibit protein synthesis in the reticulocyte lysate provided no Ca2+ was present.”
“F.A. Cotton, which has determined the three-dimensional structure of nuclease at high resolution.”
“In recent years, Anfinsen has devoted himself primarily to comprehensive investigations of an extracellular nuclease of”
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