Definitions
American Heritage® Dictionary of the English Language, Fourth Edition
- The mainland part of Equatorial Guinea, on the Bight of Biafra in western Africa.
Examples
“Porteu F, Sanchez E, Nathan CF (1990) Downregulation of tumor necrosis factor receptors on macrophages and endothelial cells by microtubule depolymerizing agents.”
“Downregulation of XIAP resulted in activation of caspase-3 and caspase-9 to trigger apoptosis in glioma cells.”
“Downregulation of MMP-9, uPAR, and CB inhibited matrigel invasion, in vitro angiogenesis and wound-healing migration ability of PC3 and DU145 prostate cancer cell lines.”
“Downregulation of BMI1 by Mel-18 overexpression or knockdown of BMI1 expression in gastric cancer cell lines led to upregulation of p16 (p16INK4a or CDKN2A) in p16 positive cell lines and reduction of phospho-AKT in both p16-positive and p16-negative cell lines.”
“Downregulation of BMI1 was also accompanied by decreased transformed phenotype and migration in both p16 - positive and p16-negative gastric cancer cell lines.”
“Chibalin AV, Leng Y, Vieira E, Krook A, Bjornholm M, et al. (2008) Downregulation of diacylglycerol kinase delta contributes to hyperglycemia-induced insulin resistance.”
“Figure 4: Downregulation of APT1 increases the steady-state palmitoylation level of Ras.”
“Downregulation of miR-132 is consistent with our finding that preconditioning ischemia induces a rapid increase in MeCP2 protein, but not mRNA, in mouse cortex.”
“Chow JM, Liu CR, Lin CP, Lee CN, Cheng YC, et al. (2008) Downregulation of c-Myc determines sensitivity to 2-methoxyestradiol-induced apoptosis in human acute myeloid leukemia.”
“Downregulation of these receptors with age explanations for all such perceived differences.”
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