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Definitions

American Heritage® Dictionary of the English Language, Fourth Edition

  1. n. A chronic disease of adults marked by enlargement of the bones of the extremities, face, and jaw that is caused by overactivity of the pituitary gland.

Century Dictionary and Cyclopedia

  1. n. A disease characterized by hypertrophy of the bones and soft tissues of the face and extremities. It is thought to be due, possibly, to a morbid change in the internal secretion of the pituitary body, since this structure is also enlarged. Most of the so-called ‘giants’ owe their size to this disorder. Also called Marie's disease.

Wiktionary

  1. n. pathology A chronic disease marked by enlargement of the bones of the extremities, face, and jaw that is caused by over-activity of the pituitary gland.

GNU Webster's 1913

  1. n. (Med.) Chronic enlargement of the extremities and face.

WordNet 3.0

  1. n. enlargement of bones of hands and feet and face; often accompanied by headache and muscle pain and emotional disturbances; caused by overproduction of growth hormone by the anterior pituitary gland (due to a tumor)

Etymologies

  1. French acromégalie, from New Latin acromegalia, from Ancient Greek ἄκρον (akron, "tip, extremity") and μέγας (megas, "large"). acro- + -megaly (Wiktionary)
  2. French acromégalie : Greek akron, top, extremity (from neuter of akros, extreme; see acro-) + Greek megas, megal-, big; see meg- in Indo-European roots. (American Heritage® Dictionary of the English Language, Fourth Edition)

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‘acromegaly’ has been looked up 2257 times, loved by 1 person, added to 14 lists, and has a Scrabble score of 18.