American Heritage® Dictionary of the English Language, Fourth Edition
- n. Total loss of vision, especially when occurring without pathological changes to the eye.
Century Dictionary and Cyclopedia
- n. A partial or total loss of sight independent of any discoverable lesion in the eye itself: formerly and still sometimes called gutta, serena; by Milton “a drop serene,” P. L., iii. 25.
- n. Any form of blindness that is accompanied to no obvious change to the eye; often the result of disease of the optic nerve
GNU Webster's 1913
- n. (Med.) A loss or decay of sight, from loss of power in the optic nerve, without any perceptible external change in the eye; -- called also
gutta serena, the “ drop serene” of Milton.
- n. partial or total loss of sight without pathology of the eye; caused by disease of optic nerve or retina or brain
- Greek amaurōsis, from amauros, dark. (American Heritage® Dictionary of the English Language, Fourth Edition)
“So, too, I said I would treat a negative disease, such as amaurosis or torpidity of liver, with the negative pole, placing the positive pole on either some healthy or morbidly positive part.”
“In 'amaurosis', the eye is beautifully clear, and, for a little while, this clearness imposes upon the casual observer; but there is a peculiar pellucid appearance about the eye -- a preternatural and unchanging brightness.”
“Haas was born with a kind of degenerative blindness called Leber's congenital amaurosis.”
“Last fall, a team led by researchers at Children's Hospital of Philadelphia and University of Pennsylvania School of Medicine reported they had successfully injected a gene via a genetically engineered vector into the retinas of 12 patients suffering from a blindness-causing genetic disease called Leber's congenital amaurosis.”
“Susan Robinson, chief executive officer of Seattle-based Targeted Genetics Corp., which is involved in an ongoing gene-therapy trial in Britain for Leber's congenital amaurosis.”
“There has been a lot of ink recently about a new study where researchers used gene therapy to restore sight to patients suffering from a rare form of congenital blindness known as Leber congenital amaurosis.”
“About 2,000 people in the U.S. have Leber's congenital amaurosis No. 2, caused when a child inherits a certain flawed gene from both parents.”
“Although the patients had a rare form of blindness called Leber's congenital amaurosis, researchers believe the approach can ultimately be used for a broad spectrum of disorders, including retinitis pigmentosa and macular degeneration.”
“But suppose I do what nearly all of the doctors do, who use electricity with any regard to polarity; that is, if treating acutely inflamed eyes, for example, apply the negative pole to the eyes, thinking thereby to make them more negative; or, if treating amaurosis, apply the positive electrode to the affected parts, thinking thereby to make them more positive!”
“Simple glaucoma, 104 cases; improvement, O. 96 per cent; condition as before, 10.5 per cent; deterioration, 52 per cent; amaurosis, 36.5 per cent.”
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