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Definitions

American Heritage® Dictionary of the English Language, Fourth Edition

  1. n. Slang A highly intelligent person: "These companies are not hot Silicon Valley startups swarming with Gen-X brainiacs” ( Ronald Henkoff).

Wiktionary

  1. n. a very intelligent and usually studious, erudite person, can be derogatory http://www.urbandictionary.com/define.php?term=Brainiac

WordNet 3.0

  1. n. someone who has exceptional intellectual ability and originality

Etymologies

  1. Probably from Brainiac, a highly intelligent villain in DC Comics, blend of brain and maniac.

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‘brainiac’ has been looked up 893 times, added to 12 lists, and has a Scrabble score of 12.