from The American Heritage® Dictionary of the English Language, 4th Edition
- n. Weight loss, wasting of muscle, loss of appetite, and general debility that can occur during a chronic disease.
from Wiktionary, Creative Commons Attribution/Share-Alike License
- n. A systemic wasting of muscle tissue, with or without loss of fat mass, that accompanies a chronic disease
from the GNU version of the Collaborative International Dictionary of English
- n. A condition of ill health and impairment of nutrition due to impoverishment of the blood, esp. when caused by a specific morbid process (as cancer or tubercle).
from The Century Dictionary and Cyclopedia
- n. Same as cachexy.
from WordNet 3.0 Copyright 2006 by Princeton University. All rights reserved.
- n. any general reduction in vitality and strength of body and mind resulting from a debilitating chronic disease
About half of all cancer patients eventually suffer serious weight loss and malnutrition, a wasting syndrome called cachexia where they don't just lose excess fat but vital muscle.
The syndrome called cachexia is responsible for between one-fifth and one-third of all cancer deaths.
I know cigarettes cause cancer, but cancer causes cachexia, which is massive weight loss and appetite loss.
Maxine Lee, 39, died of meningitis, but a wasting syndrome called "cachexia" contributed to the death, according to the death certificate.
Muscle wasting - called cachexia - is thought to account for about 30 percent of deaths in patients with cancer, but how exactly cachexia is spurred by cancer - or indeed exactly how it leads to a patient's decline - isn't known.
Ostarine is believed to increase lean body mass and improve muscle strength and performance in post-menopausal women, elderly men and men and women with cancer cachexia, which is body wasting brought on by cancer.
"Reacquiring Ostarine moves us toward this objective by allowing us to advance our lead SARM into Phase III clinical studies in cancer cachexia, which is a large commercial opportunity for our company and a critical unmet medical need for cancer patients."
While the decision to end the collaboration was mutual, it clears the way for GTx to move into phase three development of Ostarine, an oral drug that is believed to increase lean body mass and improve muscle strength and performance in post-menopausal women, elderly men and men and women with cancer cachexia, which is body wasting brought on by cancer., with Merck investing $55 million over the first three years of the deal.
Jan 21, 2009 | not rated yet | no comments yet Doctors are not doing enough to pick up on problems with excessive weight loss, says a Saint Louis University physician who helped draft recent guidelines to diagnose the condition called "cachexia"
"L.D-4033 has shown an excellent SARM profile to date in terms of efficacy, potency and selectivity, and it is potentially a novel therapeutic for muscle and bone-related disorders such as cachexia and frailty," said John L. Higgins, President and Chief Executive Officer of L.gand Pharmaceuticals.
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